We are researching methods for determining the level of oxygen delivery to different organs and in cancer.

Oxygen-ehnanced MRI

OE-MRI allows us to monitor oxygen delivery to participants using MRI. Individuals breathe elevated levels of oxygen while being scanned and we monitor the impact of oxygen on organs using a range of MRI and analysis methods. Oxygen itself is not MRI-visible, but its influence on tissue water can be monitored.

Lungs

We use T1-weighted and T2*-weighted MRI to assess the delivery of oxygen to the lungs. This provides information on ventilation, gas transfer, and perfusion.

Cancer

Oxygen-enhanced MRI allows the hypoxic status of tumours to be assessed. We use T1-weighted MRI to identify regions within tumours with different degrees of oxygen delivery and perfusion.